Manjit Sangha, who worked seven days a week before her illness, returned home on a Sunday afternoon in July last year, feeling unwell.
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1. 选基准：随机选一个元素作为基准(pivot)
在CNP类似物赛道，Ascendis的TransCon-CNP率先实现了剂型升级。与Vosoritide不一样的设计是TransCon-CNP被一层保护分子包裹，降低了体内清除影响，延长作用时间，实现每周一次给药。非头对头临床数据显示，TransCon-CNP每年2.29厘米的增高表现也优于Vosoritide。